2020 is an 'exceptional' year in many ways. The global health crisis is rapidly changing our personal and professional lives in ways we would have never imagined in 2019. At BioNotus, we have continued to provide the best service to our customers, thereby contributing the the philosophy to never waste a good crisis…

On May 4th, 2020, BioNotus hosts a company visit by a group of Master students in the context of their training as Master in Industrial Pharmacy. Despite the corona-related measures, BioNotus delivers an exciting and interactive webinar, showcasing its activities in the fields of bioanalysis and pharmacometrics.

On March 11th, Prof. Pieter Annaert gave a webinar, hosted by GMP (Groupe Métabolisme et Pharmacocinetique), entitled: "PBPK models: mechanistic plausibility drives predictive performance".

At the GMP annual meeting in Lyon, on October 16th, 2019, Prof. Pieter Annaert delivered a seminar entitled: "In vitro approaches to predict transporter-related drug-drug interactions".

On October 14th, in the context of a visit to the University of Parma, Prof. Pieter Annaert delivered a seminar entitled: "Utility of hepatocyte-based models in drug-induced cholestasis".

On October 3rd, Prof. Pieter Annaert delivered a webinar as part of a workshop organised by Altertox in collaboration with the University of Wageningen. The title of his webinar was: "PBPK modelling in pharmaceutical industry".

10th Juvenile Toxicology Symposium, Beerse, Belgium, April 25-26, 2019

2000-2020: two decades of maturing science in ontogeny of ADME proteins

From awareness towards mechanistic understanding and prediction

MCB Seminar - The Medicinal Chemistry & Bioanalysis Program GUIDE - Graduate School for Drug Exploration
University of Groningen, The Netherlands
March 26th, 2019

In vitro Detection and Exploration of Drug-Induced Cholestasis: Utility of Hepatocyte-based Models

On October 4th and 5th, Altertox academy organised a KU Leuven-hosted workshop entitled: PBPK modelling for quantitative in vitro-in vivo extrapolation.

Trainers were from KU Leuven, Wageningen University, JRC and Certara.

Full programme

Between October 15th and 18th, BioNotus sponsored and attended the 20th International Congress on In vitro Toxicology, which took place in Berlin, Germany. The topic of the meeting was: New approach methodologies for in vitro toxicology applications.

Prof. Annaert, co-founder and scientific advisor of BioNotus, delivered a lecture entitled "Simulating foetal drug exposure: sildenafil as an example".

Scientific programme

Between June 23rd and 27th, BioNotus co-founder and scientific advisor Prof. Pieter Annaert, attended the 58th Annual Meeting of the Teratology Society, which took place in Clearwater, Florida this year. The topic of the meeting was: Mechanisms, Models, Mothers and Babies: Bringing Birth Defects Research into Practice.

Prof. Annaert delivered a lecture as part of the ILSI HESI symposium "Neonatal Paediatric Drug Development". The title of his lecture was: "Pharmacokinetics in Nonclinical Models and Translation to the Clinic: Challenges and Future Directions"

Between May 27th and June 1st, BioNotus participated in the annual PAGE meeting, which took take place in Montreux (CH).

BioNotus CSO Dr. Eef Hoeben presented a poster entitled: Modelling the Transfer of Sildenafil Across the Placenta with Data of an Ex-Vivo Human Placenta Perfusion Experiment.

Link to PAGE abstracts.

Between April 20th and 25th, BioNotus co-founder and scientific advisor Prof. Pieter Annaert, together with members of his academic research team, participated in the annual Experimental Biology (EB) meeting in San Diego, California.

Annual scientific meeting on “Application of Toxicokinetics and Exposure Assessment in Toxicology and Ecotoxicology”

Including a lecture by BioNotus co-founder Prof. Pieter Annaert:
Role of hepatic transport proteins in hepatic drug disposition, hepatotoxicity and drug-drug interactions.

Dag van de Wetenschap op 26 november 2017.
BioNotus opent zijn deuren voor het brede publiek

BioNotus zet zijn wetenschappelijke activiteiten in de kijker.

We zetten met veel plezier de deur voor jullie open (10h -16h)

Een hapje en een drankje zijn te verkrijgen aan Coffee Bar Harriet.

Iedereen is van harte welkom !
Het BioNotus Team

EBF 10th Open Meeting:
A New Journey begins

15th-17th November 2017

Barcelona, Spain