Bart Lammens joined BioNotus from 1st October 2018. He studied Pharmaceutical Sciences, option Drug Development at the KU Leuven and graduated as a Pharmacist in 2015. Bart completed an additional master Industrial Pharmacy including an internship at UCB Pharma in Braine-l’Alleud and an education program between the KU Leuven, University of Antwerp, Ghent University and VUB. As an Industrial Pharmacist, Bart did additional research work at the KU Leuven Drug Delivery and Disposition lab. His research was focused on formulation development of fixed dose combinations. During his research project, he mainly used bead coating as a formulation development technique. He further applied various lab analytical techniques including solid state analysis (mDSC and PXRD), release tests in USP II and LC-UV.
Thomas Bouillon is both a physician (board certified anesthesiologist) and expert pharmacometrician. His major contributions to the field of anesthesia are a clinically relevant model of drug induced respiratory depression and the "Smart Pilot TM" display system, which visualizes drug interactions at the point of care and is implemented in high end Draeger anesthesia workstations. In 2007 he joined Modeling&Simulation at Novartis as a senior expert modeler, later associate director. In this position he introduced cumulative kill as standard metric into the Novartis malaria portfolio. In 2015 he left Novartis due to a value conflict in the KAE609/cipargamin program. From 2016-2019 he worked as Associate Professor Pharmacometrics (PMX) at the department of Pharmaceutical Sciences, KU Leuven, successfully building a Pharmacometrics Lab de novo. His team, supported by a fwo/tbm grant, developed open source software, aiming at making PMX knowledge accessible for physicians at the bedside at no cost (TDMore R-package, currently not publicly available). Having been denied tenure despite 2 positive evaluations by the responsible "beoordelingscommissie", he joined Bionotus 20191201 as senior pharmacometrician.
Yeghig Armoudjian obtained his Master degree in Chemical technologies in Armenia. Since 2014, Yeghig ambitiously worked to develop and validate more than fourteen bioanalytical methods (in accordance with FDA and EMA guidelines), for the determination of pharmaceuticals in human plasma using UHPLC - MS/MS. These methods were applied to analyse clinical samples for pharmacokinetic and pharmacodynamic studies. Yeghig's chemistry background and his determined work in the laboratory resulted in faster and more robust sample preparation techniques. Yeghig gained extensive troubleshooting skills while working with Sciex TQ MS/MSs, as well as Agilent and Shimadzu UHPLCs: these highly sensitive instruments need abundant care, to ensure continuous system performance, while obtaining reliable data and safeguarding instrument longevity. While working in a regulated environment, Yeghig adhered to the principles of GLP in all his laboratory activities. Some of Yeghig's activities have been published in highly ranked scientific journals.
Johan Van Daele got his master degree in pharmacy at Katholieke Universiteit Leuven (Belgium). He has more than 20 years experience in the field of pharmacy, research and development of drugs, food supplements and cosmetics. He developed a passion for really helping people and making the difference where he can, in his pharmacy as well as in a Congo based NGO where he acts as public health coach. He had the opportunity of experiencing entrepreneurship and management at C&J Laboratories, where he is also in charge of R&D.
Johan is happily married with Ann, and they are blessed with 2 wonderful children: Hanne-Elisabeth and Simon-Elias.
Pieter Annaert is Professor at the Drug Delivery and Disposition lab of the KU Leuven department of Pharmaceutical and Pharmacological Sciences. His research in the field of mechanistic pharmacokinetics focuses on hepatobiliary drug disposition, drug transporters, drug-induced hepatotoxicity, pediatric drug development and physiologically-based pharmacokinetic (PBPK) modelling.
After graduation as a Pharmacist in 1994 (KU Leuven), Dr. Annaert obtained his PhD from the same university in 1998, and did a 2-year postdoctoral fellowship at the University of North Carolina at Chapel Hill.
Subsequently, he held the positions of Scientist and Senior Scientist (2001-2005) at the Department of Preclinical Pharmacokinetics of Johnson & Johnson PRD.
Prof. Annaert joined the KU Leuven Drug Delivery and Disposition lab in October 2005, where he is currently supervising a group of 4 PhD researchers. In the past 10 years, he has (co)-supervised 13 PhD researchers. Prof. Annaert has co-authored 120 research articles and currently serves on the editorial boards of Drug Metabolism and Disposition and Journal of Pharmaceutical Sciences. For many years, Prof. Annaert has been teaching courses on pharmacokinetics, drug development and drug compounding. Since 2014, he is program director for the Bachelor and Master programs in Pharmaceutical Sciences at KU Leuven.