Bioanalysis | Bioanalytics | Bioanalytical services | Pharmacokinetics | Therapeutic Drug Monitoring | Analytical chemistry | Biochemistry | Clinical chemistry | Liquid chromatography | Mass spectrometry | LC-UV | LC-FLUO | UPLC | LC-MSMS | Plate reader- based assays | Stability studies | Biomarkers | Custom method development | Method validation | GCLP | Quantitative sciences | Lower limit of quantification
Short turnaround times
BioNotus has flexibility to quickly increase capacity to meet the most stringent deadlines
BioNotus is specialized in custom method development for bioanalysis
Bioanalysis encompasses the quantitative determination of analyte concentrations in biological matrices. To achieve this capability, BioNotus develops, validates and applies robust bioanalytical methods based on state-of-the-art analytical chemistry technologies. Bioanalytical methods, are analyte, matrix and application-specific.
Analytes
Types of analytes include therapeutic drugs (medicines) and their metabolites or degradation products, endogenous compounds (like for instance bile acids), as well as environmental pollutants or natural substances (some of which also have therapeutic potential).
Matrices
Biological matrices include body fluids such as blood, plasma, serum, urine, saliva, bile, cerebrospinal fluid, but also tissue homogenates, cell culture media and cell culture lysates.
Applications
Applications of bioanalytical services vary between drug discovery research over preclinical studies to First-in-Human (FIH) clinical studies, phase 2/3 clinical trials and bioequivalence studies.
Fit-for-purpose also means fit-for-budget
The bioanalysts at BioNotus are specialized in custom bioanalytical method development to address the fit-for-purpose needs of customers. Method development is always followed by context-of-use validation according to ICH/EMA and FDA guidelines.
